Project Lyme strives to end the epidemic
of tick-borne diseases. We work tenaciously
- Funding cutting-edge research
- Educating the public with accurate information
- Advocating for meaningful solutions
- Supporting patients through their Lyme Journey
We know money going to science is what will solve this epidemic, but to get to the money, we need large scale awareness and educational opportunities. We also need advocacy at an individual & governmental level. We believe the coordination of all four through organizational partnerships, plus working with doctors and researchers will help Project Lyme to solve this problem.
Jennifer Weis, Board Co-Chair
Keeping Things Current
Project Lyme’s weekly newsletter ‘Lyme Notes’ provides access to timely news, discoveries, and research developments within the Lyme world.
Nan Kurzman, Board Co-ChairJoin Our Newsletter
Educating Our Constituents
In the virtual world of 2020, Project Lyme had to adapt its practices to be able to educate our constituents. We produced educational video content viewed by over 100,000 individuals across numerous media platforms.
Kim Dickstein, Marketing CommitteeWatch Our Videos
Lighting New York City Green with The Helmsley Building
The building lighting is a dream come true. It signifies to people around the world that Lyme disease patients are all around us. They are our friends, family, and neighbors, and they need our help. The lighting has the potential to educate anyone who is less familiar with Lyme and other tick-borne diseases.
Brooke Stoddard, Board Member and Founder of Generation LymeLEARN MORE
Project Lyme awarded $100,000 to filmmaker Sini Anderson for her documentary “So Sick” which follows the journey of four women suffering from Lyme disease who are struggling to be heard by the medical community.
Project Lyme is a founding charter member of the advocacy group Center for Lyme Action. We founded the organization in partnership with Bay Area Lyme, Alexandra Cohen, and Laure Woods in order to make legislative progress with the federal government.
In 2019, Generation Lyme hosted 17 events nationally. Forced to go virtual in early 2020 because of the COVID-19 pandemic, the initiative quickly adapted to hosting Zoom Meet-ups. Since then, Generation Lyme has expanded rapidly, having hosted 250+ meetups with 3,000+ attendees.
Research for a Cure
- Brian R Crane, PhD, Cornell University, is focused on identifying an antimicrobial treatment by inhibiting the spirochete flagella hook cross-linking mechanism.
- Yuko Nakajima, PhD, Brandeis University, focuses on blocking immune evasion by Borrelia burgdorferi and other pathogens through gene conversion. Gene conversion was recently shown to be instrumental in Borrelia burgdorferi’s ability to change its surface proteins and thus keep the immune system from manufacturing antibodies.
- Geetha Parthasarathy, PhD, Tulane University, is focused on developing therapeutics for Lyme neuro-borreliosis. She will evaluate fibroblast growth factor receptor (FGFR) inhibitors as therapeutic approaches. FGFR may mediate inflammation in the central nervous system and could be a supplemental therapy in acute Lyme neuro-borreliosis.
- Michal Caspi Tal, PhD, Stanford University, explores if B. burgdorferi has a CD47 mimic and, if so, will determine the structure and sequence of that protein. She will examine how CD47 binds to the immune cell receptor and screen compounds that may be able to block this interaction so immune cells can eliminate B. burgdorferi.
- Yong Zhou, PhD, Institute for Systems Biology, explores the host response during acute and prolonged exposure to Borrelia burgdorferi with an emphasis on acute-phase proteins expressed in organs and tissues affected during infection.
- Artem Rogovskyy, DVM, Ph.D., DACVM, Texas A&M University, is working to develop a robust, rapid diagnostic test that would surpass any of the existing Lyme disease diagnostic assays in its sensitivity and specificity.
- Janakiram Seshu, PhD, University of Texas at San Antonio, aims to use a variety of cutting-edge technologies that are directed at limiting or eliminating the survival and transmission of Lyme disease pathogen between ticks and reservoir hosts such as small rodents that sustain pathogen life cycle in nature.
- Flightpath Biosciences, Inc, will study clinical biomarkers for Persistent Lyme Disease (PLD). Recent research at Northeastern University has shown that changes in the bacteria in the gastrointestinal tract may be predictive of PLD, which could lead to new tests.
- William Robinson, MD, PhD, Stanford University, studies the molecular mechanisms of autoimmune diseases and develops therapies to treat them.
We collaborate with Bay Area Lyme because of its rigorous science agenda. Project Lyme is excited to have contributed funds cutting edge research through to these multi-year projects which they manage and look forward to sharing the findings with our community. We are grateful for this partnership which continues to demonstrate progress against tick-borne diseases, one of the most important health crises of our time.