Symptom Questionnaire

MSIDS refers to Multiple Systemic Infectious Disease Syndrome (MSIDS). This term is used to describe a “symptom complex” that can create persistent and tenacious illness. Project Lyme has partnered with creator of MSIDS, Dr. Richard Horowitz, M.D., a board-certified internist, renowned Lyme disease specialist, author, and researcher, to bring you an interactive questionnaire to track your symptoms and potential risk factors for exposure to Lyme disease.


The range of Lyme symptoms is expansive, and trying to figure out what’s wrong can be overwhelming. Persistent, chronic symptoms of Lyme disease can be life-altering and have a devastating impact on your quality of life.

Published in peer-reviewed medical journals, the MSIDS model is a 38-point assessment to identify sources of infections, immune dysfunction, and inflammation contributing to your illness. After you’ve filled out the questionnaire, you can have the report emailed to you to print off and take with you when you visit your healthcare provider and begin the journey to feeling better.

The Horowitz Lyme-MSIDS Questionnaire is not intended to replace the advice of your own physician or other medical professional. You should consult a medical professional in matters relating to health, and individuals are solely responsible for their own health care decisions regarding the use of this questionnaire. It is intended for informational purposes only and not for self-treatment or diagnosis.